Myosin trapped but not tamed

Separate but not equal: differential mechanical roles for Myosin isoforms.

Cells undergo many structural-mechanical changes as an inextricable component of cellular motility, cytokinesis, and changes in cell shape. The mere act of receptor-mediated adhesion to extracellular matrix involves massive changes in cytoskeletal organization, spreading, and flattening of cells against the matrix, and the generation of traction forces through the contractile activity of cells....

not intervention but participation

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Leprosy Tamed

trigeminal neuralgia-divided but not classified

Tail chimeras of Dictyostelium myosin II support cytokinesis and other myosin II activities but not full development.

Dictyostelium lacking myosin II cannot grow in suspension culture, develop beyond the mound stage or cap concanavalin A receptors and chemotaxis is impaired. Recently, we showed that the actin-activated MgATPase activity of myosin chimeras in which the tail domain of Dictyostelium myosin II heavy chain is replaced by the tail domain of either Acanthamoeba or chicken smooth muscle myosin II is u...